Main Cast :-
John Krasinski as Reed Richards/Mr.Fantastic
Miles Teller as Teenage Reed Richards
Emily Blunt as Sue Storm/Invisible Woman
Dacre Montgomery as Johnny Storm/Human Torch
Ebon Moss-Bachrach as Ben Grimm/The Thing
Danny DeVito as Harvey Elder/Mole Man
Cillian Murphy as Victor Von Doom/Doctor Doom
Harris Dickinson as Ben Grimm (Young/College Age)
Reed's Family:
Lea Thompson as Dr. Evelyn Richards (Reed's Mother)
Eric McCormack as Dr. Nathaniel Richards (Reed's Father)
Gary Coleman as Gary Richards (Reed's Uncle)
Amy Ryan as Mary Richards (Reed's Aunt)
Millicent Simmonds as Enid Richards (Reed's Cousin, Age 12-15)
Jacob Tremblay as Danny Richards (Reed's Cousin, Age 10-13)
Julia Butters as Hope Richards (Reed's Cousin, Age 8-11)
Other MDCCU Connections:
Stan Lee as Coach Peterson (Cameo)
John Wesley Shipp as Jay Garrick/The Flash
Robert Downey Jr. as Tony Stark/Iron Man
Don Cheadle as James "Rhodey" Rhodes/War Machine
Edi Gathegi as Michael Holt/Mr. Terrific
Guy Pearce as Aldrich Killian
Mark Ruffalo as Dr. Bruce Banner
Liv Tyler as Dr. Betty Ross
Eliza Coupe as Dr. Abigail Brand (SWORD)
Storm Family:
Connie Britton as Mary Storm (Sue & Johnny's Mother)
Denis O'Hare as Franklin Storm (Sue & Johnny's Father)
Carla Gugino as MaryGay Dickins (Sue & Johnny's Aunt)
MIT/Columbia Faculty & Researchers:
David Strathairn as Professor Williams
Peter Sarsgaard as Bentley Wittman/Wizard
William H. Macy as Julius/Mad Thinker
Rainn Wilson as George Tarleton
Betsy Brandt as Dr. Sarah Johnson (Mount Sinai Hospital)
Brian Cox as Dr. Morrison (NASA)