Perhaps it's through some kind of yet unknown environmental sensors, sensing changes in temperature, pH value, or mechanical pressure. When the living environment is harsh, it actively modifies the cell's apoptosis program, allowing the virus to induce the disintegration of host cells under specific conditions.
The connexins in the vascular endothelial cells of biological samples are degraded, leading to a rapid increase in vascular permeability. The receptors on the cell membranes of platelets and blood cells are covered by viral proteins, causing these cells to lose their normal adhesion functions. Finally, the virus releases some kind of apoptosis-inducing factor, prompting the host cells to actively disassemble.
