Spiritual Energy is a wonderful thing. It shook the second law of thermodynamics, making life more likely to emerge; it enabled people to bypass theories more easily and acquire various Divine Skills. However, it was also hindering the development of science.
In this universe where Spiritual Energy existed, "Independent Self-Transcendence" and the path of the Modern Cultivator were contradictory. This was not determined by the subjective will of Immortals or mortals, but by the "Spiritual Energy" as a physical quantity and the highest instinct of "prolonging life," embedded in the deep codes of the universe.
Perhaps the vast majority of Immortals had no subjective malice toward mortals, and many might even harbor subjective goodwill, much as some Earth people embraced eco-terrorism. But they were transcended Immortals, and that fact would not change.
They were too powerful.