Zhang Zhongjing widely collected medical prescriptions and wrote the monumental work "Treatise on Cold Pathogenic and Miscellaneous Diseases." The principle of syndrome differentiation and treatment established by it is the basic principle of clinical traditional Chinese medicine, and it is the soul of traditional Chinese medicine.
At that time, the Zhang Family was among the Five Great Divine Medical Families of the Imperial Capital.
However, due to a medical incident, the Zhang Family's status declined, and they were eventually removed from the Four Great Divine Medical Families.
It was during the treatment of an extremely important person, conducted by Zhang Xi's parents. During acupuncture, an acupoint mistake led to the death of the important person. Because of this, Zhang Xi's parents both took poison and committed suicide. The entire Zhang Family was left with only Zhang Zhiyou and Zhang Xi, the grandfather and granddaughter, to manage affairs.
